R&D

R&D

논문 및 인증

Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford Progeria Syndrome
-
Communications Biology
4(1):5, 2021

Interruption of progerin–lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype
-
Journal of Clinical Investigation
126(10):3879-3893, 2016

Synthesis and evaluation of (+)-decursin derivatives as inhibitors of the Wnt/β-catenin pathway
-
Bioorg Med Chem Lett
26(15):3529-32. 2016

Anti-proliferative activity of CGK012 against multiple myeloma cells via Wnt/β-catenin signaling attenuation
-
Leukemia Research
60; 103-108, 0145-2126

Inhibiting DX2-p14/ARF Interaction Exerts Antitumor Effects in Lung Cancer and Delays Tumor Progression
-
Cancer Research
76(16):4791-804, 2016

Decursin inhibits cell growth and autophagic flux in gastric cancer via suppression of cathepsin
-
American Journal of Cancer Research
2021;11(4):1304-1320

Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm
-
Nano Today
2021, 38:101149-101158

The decursin analoge, CYJ-27, suppresses inflammation via the downregulation of NF-κB and STAT-1
-
Journal of Medicinal Food
24(8): 852-859, 2021

Ginsenoside Rg4 enhances the inductive effects of human dermal papilla spheres on hair growth via the AKT/GSK-3β/β-catenin signaling pathway
-
Journal of Microbiology and Biotechnology
2021.31(7), 933-941

PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses
-
Biomaterials
2021, 273, 120827-41

The decursin analoge, CYJ-27, suppresses inflammation via the downregulation of NF-κB and STAT-1
-
Journal of Medicinal Food
2021, 24(8), 852-859

Decursin inhibits cell growth and autophagic flux in gastric cancer via suppression of cathepsin
-
American Journal of Cancer Research
2021, 11(4), 1304-1320

Rgx365, A Rare Protopanaxatriol-Type Ginsenoside Fraction from Black Ginseng, Suppresses Inflammatory Gene iNOS via the Inhibition of p-STAT-1 and NF-κB
-
American Journal of Chinese Medicine
2020, 48(5), 1091-1102

Characterization of CGK012 in rat plasma by high performance liquid chromatography and mass spectrometry (HPLC–MS/MS): Application to a pharmacokinetic study
-
Journal of Pharmaceutical and Biomedical Analysis
2020, 189, 113458-113461

Biotransformation of Major Ginsenoside Rb1 to Rd by Dekkera anomala YAE-1 fromMongolian Fermented Milk (Airag).
-
Journal of Microbiology and Biotechnology.
2020, 30(10): 1536–1542

Inhibitory effects of protopanaxatriol type ginsenoside fraction (Rgx365) on particulate matter-induced pulmonary injury
-
Journal of Toxicology and Environmental Health-Part A
2019, 82(5), 338-350

Suppressive activities of RGX-365 on HMGB1-mediated septic responses,
-
Biochemical Pharmacology
2019, 163, 260-268

Suppressive Effects of Ginsenoside Rh1 on HMGB1-Mediated Septic Responses,
-
American Journal of Chinese Medicine
2019, 47(1), 119-133.

Inhibitory effects of protopanaxatriol type ginsenoside fraction (Rgx365) on particulate matter-induced pulmonary injury
-
Journal of Toxicology and Environmental Health-Part A
2019. 82(5), 338-350.

Suppressive effects of rare ginsenosides, Rk1 and Rg5, on HMGB1mediated septic responses,
-
Food and Chemical Toxicology
2019, 124, 45-53. 3.

Pulmonary protective functions of rare ginsenposide Rg4 on particulate matter-induced inflammatory responses
-
Biotechnology and Bioprocess Engineering
2019, 24, 445-453.

Inhibitory effects of black ginseng extract on particulate matter-induced pulmonary injury,
-
American Journal of Chinese Medicine
2019, 47(6), 1237-1251

Prevention effect of rare ginsenosides(Rg6) against stress-hormone induced MTOC amplification,
-
Oncotarget
7(23):35144-58, 2016. 2.